Yttrium in PDB 4iax: Engineered Human Lipocalin 2 (CL31) in Complex with Y-Dtpa

The structure of Engineered Human Lipocalin 2 (CL31) in Complex with Y-Dtpa, PDB code: 4iax was solved by A.Eichinger, A.Skerra, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.82 / 1.90
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	60.120, 60.120, 110.550, 90.00, 90.00, 90.00
R / Rfree (%)	19.5 / 24.5

The binding sites of Yttrium atom in the Engineered Human Lipocalin 2 (CL31) in Complex with Y-Dtpa (pdb code 4iax). This binding sites where shown within 5.0 Angstroms radius around Yttrium atom.
In total only one binding site of Yttrium was determined in the Engineered Human Lipocalin 2 (CL31) in Complex with Y-Dtpa, PDB code: 4iax:

Yttrium binding site 1 out of 1 in the Engineered Human Lipocalin 2 (CL31) in Complex with Y-Dtpa


Mono view


Stereo pair view

A full contact list of Yttrium with other atoms in the Y binding site number 1 of Engineered Human Lipocalin 2 (CL31) in Complex with Y-Dtpa within 5.0Å range: probe atom residue distance (Å) B Occ A:Y202 b:13.5 occ:1.00 O6 A:LIZ201 2.3 14.3 1.0 O8 A:LIZ201 2.4 15.4 1.0 O4 A:LIZ201 2.4 9.7 1.0 O A:HOH370 2.4 16.0 1.0 O10 A:LIZ201 2.5 12.7 1.0 O2 A:LIZ201 2.5 14.0 1.0 N2 A:LIZ201 2.6 16.3 1.0 N3 A:LIZ201 2.7 13.2 1.0 N1 A:LIZ201 2.7 13.3 1.0 C5 A:LIZ201 3.2 16.1 1.0 C1 A:LIZ201 3.2 16.7 1.0 C7 A:LIZ201 3.2 11.2 1.0 C2 A:LIZ201 3.3 14.1 1.0 C9 A:LIZ201 3.3 16.9 1.0 C3 A:LIZ201 3.3 15.7 1.0 C6 A:LIZ201 3.4 11.2 1.0 C8 A:LIZ201 3.4 9.3 1.0 C10 A:LIZ201 3.4 14.0 1.0 C13 A:LIZ201 3.4 12.6 1.0 C11 A:LIZ201 3.5 9.9 1.0 C12 A:LIZ201 3.5 15.2 1.0 C14 A:LIZ201 3.5 12.7 1.0 C4 A:LIZ201 3.5 15.7 1.0 NE2 A:GLN33 4.3 11.4 1.0 O1 A:LIZ201 4.3 15.2 1.0 O5 A:LIZ201 4.4 14.8 1.0 O7 A:LIZ201 4.4 15.5 1.0 O3 A:LIZ201 4.5 14.4 1.0 O9 A:LIZ201 4.5 15.2 1.0 O A:HOH309 4.6 12.2 1.0 O A:HOH355 4.8 34.0 1.0 C15 A:LIZ201 4.9 16.9 1.0 O A:HOH379 4.9 21.6 1.0 C18 A:LIZ201 4.9 15.2 1.0 C25 A:LIZ201 5.0 7.4 1.0

E.Eggenstein, A.Eichinger, H.J.Kim, A.Skerra. Structure-Guided Engineering of Anticalins with Improved Binding Behavior and Biochemical Characteristics For Application in Radio-Immuno Imaging and/or Therapy J.Struct.Biol. V. 185 203 2014.
ISSN: ISSN 1047-8477
PubMed: 23542582
DOI: 10.1016/J.JSB.2013.03.009