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Atomistry » Yttrium » PDB 3ph6-8pun » 5u62 » |
Yttrium in PDB 5u62: Crystal Structure of Eed in Complex with H3K27ME3 Peptide and 6- (Benzo[D][1,3]Dioxol-4-Ylmethyl)-5,6,7,8-Tetrahydroimidazo[1,5- A]Pyridin-3-AmineEnzymatic activity of Crystal Structure of Eed in Complex with H3K27ME3 Peptide and 6- (Benzo[D][1,3]Dioxol-4-Ylmethyl)-5,6,7,8-Tetrahydroimidazo[1,5- A]Pyridin-3-Amine
All present enzymatic activity of Crystal Structure of Eed in Complex with H3K27ME3 Peptide and 6- (Benzo[D][1,3]Dioxol-4-Ylmethyl)-5,6,7,8-Tetrahydroimidazo[1,5- A]Pyridin-3-Amine:
2.1.1.43; Protein crystallography data
The structure of Crystal Structure of Eed in Complex with H3K27ME3 Peptide and 6- (Benzo[D][1,3]Dioxol-4-Ylmethyl)-5,6,7,8-Tetrahydroimidazo[1,5- A]Pyridin-3-Amine, PDB code: 5u62
was solved by
D.Bussiere,
W.Shu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Yttrium Binding Sites:
The binding sites of Yttrium atom in the Crystal Structure of Eed in Complex with H3K27ME3 Peptide and 6- (Benzo[D][1,3]Dioxol-4-Ylmethyl)-5,6,7,8-Tetrahydroimidazo[1,5- A]Pyridin-3-Amine
(pdb code 5u62). This binding sites where shown within
5.0 Angstroms radius around Yttrium atom.
In total 2 binding sites of Yttrium where determined in the Crystal Structure of Eed in Complex with H3K27ME3 Peptide and 6- (Benzo[D][1,3]Dioxol-4-Ylmethyl)-5,6,7,8-Tetrahydroimidazo[1,5- A]Pyridin-3-Amine, PDB code: 5u62: Jump to Yttrium binding site number: 1; 2; Yttrium binding site 1 out of 2 in 5u62Go back to Yttrium Binding Sites List in 5u62
Yttrium binding site 1 out
of 2 in the Crystal Structure of Eed in Complex with H3K27ME3 Peptide and 6- (Benzo[D][1,3]Dioxol-4-Ylmethyl)-5,6,7,8-Tetrahydroimidazo[1,5- A]Pyridin-3-Amine
Mono view Stereo pair view
Yttrium binding site 2 out of 2 in 5u62Go back to Yttrium Binding Sites List in 5u62
Yttrium binding site 2 out
of 2 in the Crystal Structure of Eed in Complex with H3K27ME3 Peptide and 6- (Benzo[D][1,3]Dioxol-4-Ylmethyl)-5,6,7,8-Tetrahydroimidazo[1,5- A]Pyridin-3-Amine
Mono view Stereo pair view
Reference:
A.Lingel,
M.Sendzik,
Y.Huang,
M.D.Shultz,
J.Cantwell,
M.P.Dillon,
X.Fu,
J.Fuller,
T.Gabriel,
J.Gu,
X.Jiang,
L.Li,
F.Liang,
M.Mckenna,
W.Qi,
W.Rao,
X.Sheng,
W.Shu,
J.Sutton,
B.Taft,
L.Wang,
J.Zeng,
H.Zhang,
M.Zhang,
K.Zhao,
M.Lindvall,
D.E.Bussiere.
Structure-Guided Design of Eed Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase. J. Med. Chem. V. 60 415 2017.
Page generated: Sat Oct 12 20:47:03 2024
ISSN: ISSN 1520-4804 PubMed: 27992714 DOI: 10.1021/ACS.JMEDCHEM.6B01473 |
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